Collect. Czech. Chem. Commun. 2006, 71, 44-58
https://doi.org/10.1135/cccc20060044

Synthesis and Biological Evaluation of (E)-3-(Nitrophenyl)-1-(pyrazin-2-yl)prop-2-en-1-ones

Veronika Opletalováa,*, Milan Pourb, Jiří Kunešb, Vladimír Buchtac, Luís Silvac, Katarína Kráľovád, Marta Chlupáčováa, Dana Meltrováa, Milan Peterkaa and Martina Posledníkováa

a Department of Pharmaceutical Chemistry and Drug Control, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
b Department of Inorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
c Department of Biological and Medical Sciences, Faculty of Pharmacy, Charles University, Heyrovského 1203, 500 05 Hradec Králové, Czech Republic
d Institute of Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská dolina, 842 15 Bratislava, Slovak Republic

Individual author index pages


Other CCCC articles of these authors

  • Vojtěch Balšánek, Lucie Tichotová, Jiří Kuneš, Marcel Špulák, Milan Pour*, Ivan Votruba and Vladimír Buchta
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  • Marta Kučerová-Chlupáčová, Veronika Opletalová*, Josef Jampílek, Jan Doležel, Jiří Dohnal, Milan Pour, Jiří Kuneš and Viktor Voříšek
    New Hydrophobicity Constants of Substituents in Pyrazine Rings Derived from RP-HPLC Study
    2008, Vol. 73, Issue 1, pp. 1–18 [Abstract]
  • Ivan Šnajdr, Jan Pavlík, Radan Schiller, Jiří Kuneš and Milan Pour*
    Pentenolide Analogues of Antifungal Butenolides: Strategies Towards 3,6-Disubstituted Pyranones and Unexpected Loss of Biological Effect
    2007, Vol. 72, Issue 11, pp. 1472–1498 [Abstract]
  • Jiří Kuneš, Vojtěch Balšánek, Milan Pour* and Vladimír Buchta
    Synthesis and Antifungal Activity Evaluation of 3-Hetaryl-2,5-dihydrofuran-2-ones. An Unusual Fragmentation of the Oxazole Ring via 2,3-Selenoxide Shift
    2001, Vol. 66, Issue 12, pp. 1809–1830 [Abstract]
  • Karel Waisser*, Miloš Macháček, Hynek Dostál, Jiří Gregor, Lenka Kubicová, Věra Klimešová, Jiří Kuneš, Karel Palát, Jr., Jana Hladůvková, Jarmila Kaustová and Ute Möllmann
    Relationships Between the Chemical Structure of Substances and Their Antimycobacterial Activity Against Atypical Strains. Part 18. 3-Phenyl-2H-1,3-benzoxazine-2,4(3H)-diones and Isosteric 3-Phenylquinazoline-2,4(1H,3H)-diones
    1999, Vol. 64, Issue 11, pp. 1902–1924 [Abstract]
  • Věra Klimešová*, Martin Svoboda, Karel Waisser, Milan Pour and Jarmila Kaustová
    Synthesis and Antimicrobial Activity of New 4-(Benzylsulfanyl)pyridine Derivatives
    1999, Vol. 64, Issue 2, pp. 417–434 [Abstract]
  • Jiří Kuneš, Jiří Jáchym, Petr Jirásko, Želmíra Odlerová and Karel Waisser
    Combination of the Topliss Approach with the Free-Wilson Analysis in the Study of Antimycobacterial Activityof 4-Alkylthiobenzanilides
    1997, Vol. 62, Issue 9, pp. 1503–1510 [Abstract]
  • Katarína Kráľová, František Šeršeň, Věra Klimešová and Karel Waisser
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    1997, Vol. 62, Issue 3, pp. 516–520 [Abstract]
  • Martin Doležal, Jiří Hartl, Antonín Lyčka, Vladimír Buchta and Želmíra Odlerová
    Synthesis and Antituberculotic Properties of Some Substituted Pyrazinecarbothioamides
    1996, Vol. 61, Issue 7, pp. 1102–1108 [Abstract]
  • Veronika Opletalová, Asmita Patel, Michael Boulton, Alice Dundrová, Eva Lacinová, Marta Převorová, Martina Appeltauerová and Milada Coufalová
    5-Alkyl-2-pyrazinecarboxamides, 5-Alkyl-2-pyrazinecarbonitriles and 5-Alkyl-2-acetylpyrazines as Synthetic Intermediates for Antiinflammatory Agents
    1996, Vol. 61, Issue 7, pp. 1093–1101 [Abstract]
  • Karel Waisser, Jiří Kuneš, Alexandr Hrabálek, Miloš Macháček and Želmíra Odlerová
    New Groups of Potential Antituberculotics: 5-Alkylthio-1-aryltetrazoles
    1996, Vol. 61, Issue 5, pp. 791–798 [Abstract]
  • Veronika Opletalová, Jiří Hartl, Asmita Patel and Michael Boulton
    Homolytic Acetylation of 2,5-Dimethylpyrazine
    1995, Vol. 60, Issue 9, pp. 1551–1554 [Abstract]
  • Martin Doležal, Jiří Hartl, Antonín Lyčka, Vladimír Buchta and Želmíra Odlerová
    Synthesis and Antituberculotic Activity of Some Substituted 3-Arylamino-5-cyano-2-pyrazinecarboxamides
    1995, Vol. 60, Issue 7, pp. 1236–1241 [Abstract]
  • Katarína Kráľová, Dušan Loos and Jozef Čižmárik
    Quantitative Relationships Between Inhibition of Photosynthesis and Lipophilicity of Piperidinoethyl Alkoxyphenylcarbamates
    1994, Vol. 59, Issue 10, pp. 2293–2302 [Abstract]
  • Karel Waisser, Jiří Kuneš, Alexandr Hrabálek and Želmíra Odlerová
    New Groups of Potential Antituberculotics: Bis(1-aryltetrazol-5-yl) Disulfides. Structure Activity Relationship
    1994, Vol. 59, Issue 1, pp. 234–238 [Abstract]
  • Karel Waisser, Jiří Kuneš, Jiří Klimeš, Miroslav Polášek and Želmíra Odlerová
    Relations between Structure and Antituberculotic Activity of 4-Alkoxybenzoic Acids
    1993, Vol. 58, Issue 1, pp. 191–196 [Abstract]
  • Karel Waisser, Jiří Kuneš and Želmíra Odlerová
    Correlation of structural parameters with antituberculotic activity in a group of 2-benzamidobenzothiazoles
    1991, Vol. 56, Issue 12, pp. 2978–2985 [Abstract]