Collect. Czech. Chem. Commun. 2006, 71, 859-870
https://doi.org/10.1135/cccc20060859

Kinetics and Mechanisms for the Isomerization of Internucleosidic 3'-O-P-CH2-5' and 3'-O-P-CH(OH)-5' Linkages to Their 2',5'-Counterparts

Tuomas Lönnberga, Šárka Králíkováb, Ivan Rosenbergb and Harri Lönnberga,*

a Department of Chemistry, University of Turku, 20014 Turku, Finland
b Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Individual author index pages


Other CCCC articles of these authors

  • Martina Pressová, Miloš Buděšínský and Ivan Rosenberg
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    Symposium Series 1999, Vol. 2, pp. 281–282 [Abstract]
    Published online 2016-05-08 23:32:45
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    Published online 2016-05-08 23:30:57
  • Mikko Ora, Johanna Järvi, Mikko Oivanen and Harri Lönnberg
    Hydrolytic reactions of the phosphorodithioate analog of uridylyl(3',5')uridine: Cleavage, desulfurization and isomerization
    Symposium Series 1999, Vol. 2, pp. 230–232 [Abstract]
    Published online 2016-05-08 23:30:50
  • Niangoran Koissi, Kari Neuvonen, Tony Munter, Leif Kronberg and Harri Lönnberg
    A novel fluorescent base modification by reaction of guanosine with triformylmethane
    Symposium Series 1999, Vol. 2, pp. 228–229 [Abstract]
    Published online 2016-05-08 23:30:43
  • Mohamed I. Elzagheid, Kati Mattila, Mikko Oivanen, Bryan C. N. M. Jones, Richard Cosstick and Harri Lönnberg
    Hydrolytic reactions of 2',3'-dideoxy-3'-thiothymidine 3',5'-cyclic phosphorothiolate methyl ester
    Symposium Series 1999, Vol. 2, pp. 225–227 [Abstract]
    Published online 2016-05-08 23:30:36
  • Qi Wang, Satu Mikkola, Zoltan Jori, Mia Helkearo and Harri Lönnberg
    Bimetallic Ca2+ and Zn2+ complexes of BISDIEN: Potential catalysts of RNA cleavage
    Symposium Series 1999, Vol. 2, pp. 222–224 [Abstract]
    Published online 2016-05-08 23:30:30
  • Erkki J. Nurminen, Jorma K. Mattinen and Harri Lönnberg
    Catalysis in tetrazole-promoted phosphoramidite alcoholysis
    Symposium Series 1999, Vol. 2, pp. 219–221 [Abstract]
    Published online 2016-05-08 23:30:24
  • Zdeněk Točík, Ivana Kavenová and Ivan Rosenberg
    Synthetic route to novel isosteric phosphonate analogs of oligonucleotides
    Symposium Series 1999, Vol. 2, pp. 109–113 [Abstract]
    Published online 2016-05-08 20:42:08
  • Dominik Rejman, Radek Liboska, Magdalena Endová, Ivana Kavenová, Zdeněk Točík and Ivan Rosenberg
    Synthesis and hybridization properties of isopolar, nonisosteric phosphonate-based homooligonucleotides
    Symposium Series 1999, Vol. 2, pp. 96–99 [Abstract]
    Published online 2016-05-08 20:41:51
  • Dominik Rejman and Ivan Rosenberg
    Preparation of phosphonate monomers for phosphotriester solid-phase synthesis of isopolar nonisosteric oligonucleotide analogs
    Symposium Series 1999, Vol. 2, pp. 92–95 [Abstract]
    Published online 2016-05-08 20:41:45
  • Šárka Králíková, Miloš Buděšínský, Milena Masojídková, Ivana Kavenová and Ivan Rosenberg
    Synthesis of α-hydroxyphosphonate analogs of ApA and UV spectroscopy study on their complexes with poly(U)
    Symposium Series 1999, Vol. 2, pp. 89–91 [Abstract]
    Published online 2016-05-08 20:41:40
  • Markéta Rinnová and Ivan Rosenberg
    3'-N-phosphonomethyl derivatives of pyrrolidine nucleosides related to L-nucleotides
    Symposium Series 1999, Vol. 2, pp. 60–62 [Abstract]
    Published online 2016-05-08 20:41:05
  • Satu Mikkola, Izabela Zagorowska and Harri Lönnberg
    The effect of the secondary structure of RNA on the reactivity of its phosphodiester bonds: The cleavage of phosphodiester bonds within hairpin loops in the presence and absence of metal ion catalysts
    Symposium Series 1999, Vol. 2, pp. 6–10 [Abstract]
    Published online 2016-05-08 20:39:48
  • Mohamed I. Elzagheid, Esa Mäki, Ulla Kaukinen, Mikko Oivanen and Harri Lönnberg
    Hydrolysis and intramolecular transesterification of 3'-thioinosine 3'-S-phosphorothiolate triester
    Symposium Series 1999, Vol. 2, pp. 1–5 [Abstract]
    Published online 2016-05-08 20:39:38
  • Joanna Zuberek, Janusz Stępiński, Anna Niedzwiecka, Ryszard Stolarski, Harri Salo, Harri Lönnberg and Edward Darżynkiewicz
    Synthesis of tetraribonucleotide cap analogue m7GpppAm2'pUm2'pAm2' and its interaction with eukaryotic initiation factor eIF4E
    Symposium Series 2002, Vol. 5, pp. 399–403 [Abstract]
    Published online 2016-01-25 20:52:22
  • Václav Vaněk, Miloš Buděšínský, Ivana Kavenová, Markéta Rinnová and Ivan Rosenberg
    Isosteric phosphonate-pyrrolidine-based dinucleoside monophosphate analogues
    Symposium Series 2002, Vol. 5, pp. 391–392 [Abstract]
    Published online 2016-01-25 20:52:06
  • Martina Pressová, Radek Liboska, Miloš Buděšínský, Šárka Králíková, Ivana Kavenová and Ivan Rosenberg
    Oligomerisation aiming at phosphonate analogues of oligoadenylates
    Symposium Series 2002, Vol. 5, pp. 383–384 [Abstract]
    Published online 2016-01-25 20:51:50
  • Ondřej Páv, Miloš Buděšínský and Ivan Rosenberg
    2'-5' Oligoadenylate analogues with C-phosphonate internucleotide linkage
    Symposium Series 2002, Vol. 5, pp. 379–380 [Abstract]
    Published online 2016-01-25 20:51:40
  • Teija Niittymäki, Ulla Kaukinen, Pasi Virta and Harri Lönnberg
    Azacrown tethered oligonucleotides: Potential artificial RNases
    Symposium Series 2002, Vol. 5, pp. 376–378 [Abstract]
    Published online 2016-01-25 20:51:35
  • Kati Mattila, Tuomas Lönnberg, Mikko Ora, Mikko Oivanen and Harri Lönnberg
    Synthesis and hydrolytic reactions of an N3'-phosphoramidate analog of uridylyl(3',5')uridine
    Symposium Series 2002, Vol. 5, pp. 370–372 [Abstract]
    Published online 2016-01-25 20:51:23
  • Radek Liboska, Miloš Buděšínský, Ivana Kavenová, Ondřej Páv and Ivan Rosenberg
    Hybridization properties of 4'-branched oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 365–366 [Abstract]
    Published online 2016-01-25 20:51:12
  • Šárka Králíková, Miloš Buděšínský, Ivana Kavenová and Ivan Rosenberg
    α-Hydroxyphosphonate oligonucleotides: A striking DNA type?
    Symposium Series 2002, Vol. 5, pp. 356–357 [Abstract]
    Published online 2016-01-25 20:50:54
  • Kaisa Ketomäki and Harri Lönnberg
    Mixed-phase hybridization of short oligodeoxyribonucleotides on microscopic polymer particles: The effects of various one-base mismatches on the duplex stability
    Symposium Series 2002, Vol. 5, pp. 342–343 [Abstract]
    Published online 2016-01-25 20:50:31
  • Zdeněk Točík, Radek Liboska, Ivan Barvík, Jr., Miloš Buděšínský, Milena Masojídková, Ivana Kavenová and Ivan Rosenberg
    Isosteric phosphonate mono- and oligonucleotides originating from 4',5'-didehydronucleoside precursors: Some synthetic possibilities and limitations
    Symposium Series 2002, Vol. 5, pp. 208–214 [Abstract]
    Published online 2016-01-25 20:40:13
  • Ivan Rosenberg, Magdalena Endová-Petrová, Šárka Králíková, Radek Liboska, Dominik Rejman and Zdeněk Točík
    From nucleoside phosphonic acids to modified oligonucleotides
    Symposium Series 2002, Vol. 5, pp. 200–207 [Abstract]
    Published online 2016-01-25 20:40:07
  • Erkki J. Nurminen, Jorma K. Mattinen and Harri Lönnberg
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    Symposium Series 2002, Vol. 5, pp. 129–134 [Abstract]
    Published online 2016-01-25 20:39:16
  • Satu Mikkola, Ulla Kaukinen, Izabella Zagorowska and Harri Lönnberg
    The cleavage of RNA phosphodiester bonds by metal ions
    Symposium Series 2002, Vol. 5, pp. 121–128 [Abstract]
    Published online 2016-01-25 20:39:11
  • Milan Vrabel, Ivan Rosenberg and Michal Hocek
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    Symposium Series 2005, Vol. 7, pp. 485–486 [Abstract]
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  • Václav Vaněk, Miloš Buděšínský and Ivan Rosenberg
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    Symposium Series 2005, Vol. 7, pp. 483–484 [Abstract]
    Published online 2015-11-08 11:58:51
  • Zdeněk Točík, Ivan Barvík, Jr., Miloš Buděšínský and Ivan Rosenberg
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    Symposium Series 2005, Vol. 7, pp. 481–482 [Abstract]
    Published online 2015-11-08 11:58:47
  • Päivi Poijärvi and Harri Lönnberg
    Biodegradable phosphate protections of oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 457–459 [Abstract]
    Published online 2015-11-08 11:58:11
  • Ondřej Páv, Eva Protivínská, Jiří Jiráček and Ivan Rosenberg
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    Symposium Series 2005, Vol. 7, pp. 453–454 [Abstract]
    Published online 2015-11-08 11:58:03
  • Ondřej Pačes and Ivan Rosenberg
    Isopolar, isosteric 4'-substituted 2',5'-oligoadenylates as potential RNase L activators
    Symposium Series 2005, Vol. 7, pp. 447–448 [Abstract]
    Published online 2015-11-08 11:57:54
  • Teija Niittymäki and Harri Lönnberg
    Sequence-selective cleavage of oligoribonucleotides
    Symposium Series 2005, Vol. 7, pp. 443–444 [Abstract]
    Published online 2015-11-08 11:57:44
  • Radek Liboska, Ondřej Páv and Ivan Rosenberg
    Monomers for novel phosphonate oligonucleotides, potential RNase L inhibitors
    Symposium Series 2005, Vol. 7, pp. 437–438 [Abstract]
    Published online 2015-11-08 11:57:30
  • Šárka Králíková, Miloš Buděšínský, Radek Liboska, Ondřej Páv and Ivan Rosenberg
    2',5'-Linked oligo-3'-deoxynucleotide chimeras with chiral α-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?
    Symposium Series 2005, Vol. 7, pp. 421–422 [Abstract]
    Published online 2015-11-08 11:57:07
  • Petr Kočalka, Markéta Rinnová, Václav Vaněk, Dominik Rejman, Ivan Votruba, Ivana Tomečková, Šárka Králíková, Magdalena Petrová, Ondřej Páv, Radek Pohl, Miloš Buděšínský, Radek Liboska, Zdeněk Točík and Ivan Rosenberg
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    Symposium Series 2005, Vol. 7, pp. 415–416 [Abstract]
    Published online 2015-11-08 11:56:57
  • Anu Kiviniemi, Petri Heinonen and Harri Lönnberg
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    Symposium Series 2005, Vol. 7, pp. 413–414 [Abstract]
    Published online 2015-11-08 11:56:51
  • Kaisa Ketomäki and Harri Lönnberg
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    Symposium Series 2005, Vol. 7, pp. 407–408 [Abstract]
    Published online 2015-11-08 11:56:41
  • Tuomas Lönnberg, Johanna Kiiski, Jonna Korhonen and Satu Mikkola
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    Symposium Series 2005, Vol. 7, pp. 269–270 [Abstract]
    Published online 2015-11-08 11:53:43
  • Pasi Virta, Johanna Katajisto and Harri Lönnberg
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    Symposium Series 2005, Vol. 7, pp. 265–267 [Abstract]
    Published online 2015-11-08 11:53:37
  • Mikko Ora, Anu Kiviniemi, Tuomas Lönnberg, Sami Virtanen and Harri Lönnberg
    Phosphodiester cleavage of diribonucleoside 3',3'-monophosphates: Rate acceleration by the 2'-hydroxyl and 2'-amino function, implications to ribozyme action
    Symposium Series 2005, Vol. 7, pp. 261–263 [Abstract]
    Published online 2015-11-08 11:53:33
  • Ulla Pentikäinen, Mikael Peräkylä and Harri Lönnberg
    The effect of base sequence on the hydrolytic stability of RNA phosphodiester bonds
    Symposium Series 2005, Vol. 7, pp. 259–260 [Abstract]
    Published online 2015-11-08 11:53:27
  • Radek Pohl, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
    Pyrrolidine nucleotide analogues – conformation study
    Symposium Series 2005, Vol. 7, pp. 165–166 [Abstract]
    Published online 2015-11-08 11:51:48
  • Dominik Rejman, Petr Kočalka, Radek Pohl and Ivan Rosenberg
    Synthesis of 4'-N pyrrolidine nucleosides, nucleotides, and oligonucleotides
    Symposium Series 2005, Vol. 7, pp. 159–163 [Abstract]
    Published online 2015-11-08 11:51:43
  • Ivan Rosenberg, Ivan Barvik, Miloš Buděšínský, Petr Kočalka, Šárka Králíková, Radek Liboska, Ondřej Pačes, Ondřej Páv, Magdalena Petrová, Radek Pohl, Martina Pressová, Dominik Rejman, Ivan Votruba and Zdeněk Točík
    Nucleoside phosphonic acids and related oligonucleotides: Structural diversity vs biological properties
    Symposium Series 2005, Vol. 7, pp. 153–157 [Abstract]
    Published online 2015-11-08 11:51:38
  • Jiří Jiráček, Michaela Collinsová, Ivan Rosenberg, Hana Netušilová, Miloš Buděšínský and Timothy A. Garrow
    New inhibitors of human betaine-homocysteine S-methyltransferase
    Symposium Series 2005, Vol. 8, pp. 33–35 [Abstract]
    Published online 2015-11-06 12:02:21
  • Kaisa Ketomäki, Päivi-Poijärvi Virta, Qi Wang and Harri Lönnberg
    Base moiety selectivity in cleavage of short oligonucleotides by di- and trinuclear Zn(II) complexes of azacrown-derived ligands
    Symposium Series 2008, Vol. 10, pp. 437–438 [Abstract]
    Published online 2015-10-30 18:44:32
  • Radek Pohl, Miloš Buděšínský, Dominik Rejman, Petr Kočalka and Ivan Rosenberg
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    Symposium Series 2008, Vol. 10, pp. 435–436 [Abstract]
    Published online 2015-10-30 18:44:27
  • Anna Leisvuori, Päivi Poijärvi-Virta, Pasi Virta and Harri Lönnberg
    4-Oxoheptanedioic acid linker in the synthesis of base-sensitive oligonucleotides
    Symposium Series 2008, Vol. 10, pp. 401–403 [Abstract]
    Published online 2015-10-30 18:43:25
  • Teija Niittymäki, Pasi Virta, Kaisa Ketomäki and Harri Lönnberg
    Di(azacrown) conjugates of 2'-O-methyl oligoribonucleotides as sequence-selective artificial ribonucleases
    Symposium Series 2008, Vol. 10, pp. 378–379 [Abstract]
    Published online 2015-10-30 18:42:41
  • Tuomas Karskela and Harri Lönnberg
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    Symposium Series 2008, Vol. 10, pp. 372–373 [Abstract]
    Published online 2015-10-30 18:42:24
  • Marika Karskela, Pasi Virta, Melina Malinen, Arto Urtti and Harri Lönnberg
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    Symposium Series 2008, Vol. 10, pp. 369–371 [Abstract]
    Published online 2015-10-30 18:42:20
  • Qi Wang, Attila Jancsó, Teija Niittymäki, Päivi Poijärvi-Virta, Kaisa Ketomäki, Pasi Virta, Ewelina Leino, István Szilágyi, Satu Mikkola, Tamás Gajda and Harri Lönnberg
    Base and sequence selective cleavage of RNA phosphodiester bonds by Zn(II) azacrown chelates
    Symposium Series 2008, Vol. 10, pp. 63–70 [Abstract]
    Published online 2015-10-30 18:35:17
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    Symposium Series 2011, Vol. 12, pp. 462–464 [Abstract]
    Published online 2015-08-20 10:24:33
  • Magdalena Petrová, Miloš Buděšínský, Blanka Klepetářová and Ivan Rosenberg
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    Symposium Series 2011, Vol. 12, pp. 430–432 [Abstract]
    Published online 2015-08-20 10:23:23
  • Teija Niittymäki, Ekaterina Burakova, Anna Leisvuori, Pasi Virta and Harri Lönnberg
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    Symposium Series 2011, Vol. 12, pp. 411–412 [Abstract]
    Published online 2015-08-20 10:20:54
  • Anu Kiviniemi, Pasi Virta and Harri Lönnberg
    Click conjugation of 4'-C-modified oligonucleotides
    Symposium Series 2011, Vol. 12, pp. 361–363 [Abstract]
    Published online 2015-08-20 10:19:06
  • Tuomas Lönnberg, Mia Helkearo, Attila Jancsó and Tamás Gajda
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    Symposium Series 2011, Vol. 12, pp. 268–271 [Abstract]
    Published online 2015-08-20 10:10:58
  • Emilia Kiuru, Mikko Ora, Leonid Beigelman, Lawrence Blatt and Harri Lönnberg
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    Symposium Series 2011, Vol. 12, pp. 184–188 [Abstract]
    Published online 2015-08-20 10:00:37
  • Ondřej Šimák, Petr Pachl, Tomáš Jandušík, Jiří Brynda, Miloš Buděšínský and Ivan Rosenberg
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    Published online 2015-07-06 23:09:12
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    Published online 2015-07-06 23:09:07
  • Magdalena Petrová, Miloš Buděšínský, Eva Zborníková, Natalia Panova, Pavel Novák and Ivan Rosenberg
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    Symposium Series 2014, Vol. 14, pp. 348–349 [Abstract]
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    Symposium Series 2014, Vol. 14, pp. 312–313 [Abstract]
    Published online 2015-07-06 23:06:24
  • Ondřej Kostov, Eva Zborníková, Miloš Buděšínský, Pavel Novák and Ivan Rosenberg
    Sulfur-containing phosphonate monomers for oligonucleotide synthesis
    Symposium Series 2014, Vol. 14, pp. 308–309 [Abstract]
    Published online 2015-07-06 23:06:12
  • Martin Maxmilian Kaiser, Pavel Novák, Šárka Rosenbergová, Lenka Poštová-Slavětínská, Ivan Rosenberg and Zlatko Janeba
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    Symposium Series 2014, Vol. 14, pp. 293–294 [Abstract]
    Published online 2015-07-06 23:05:30
  • Tuomas Karskela*, Karel D. Klika and Harri Lönnberg
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    2011, Vol. 76, Issue 8, pp. 1043–1054 [Abstract]
  • Ivana Poláková, Miloš Buděšínský, Zdeněk Točík and Ivan Rosenberg*
    Tetrofuranose nucleoside phosphonic acids: Synthesis and properties
    2011, Vol. 76, Issue 5, pp. 503–536 [Abstract]
  • Dominik Rejman*, Petr Kočalka, Radek Pohl, Zdeněk Točík and Ivan Rosenberg*
    Synthesis and hybridization of oligonucleotides modified at AMP sites with adenine pyrrolidine phosphonate nucleotides
    2009, Vol. 74, Issue 6, pp. 935–955 [Abstract]
  • Ondřej Pačes, Zdeněk Točík* and Ivan Rosenberg*
    A New Linker for Solid-Phase Synthesis of Oligonucleotides with Terminal Phosphate Group
    2008, Vol. 73, Issue 1, pp. 32–43 [Abstract]
  • Alicja Stachelska*, Zbigniew J. Wieczorek, Janusz Stępiński, Marzena Jankowska-Anyszka, Harri Lönnberg and Edward Darżynkiewicz
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    2006, Vol. 71, Issue 4, pp. 567–578 [Abstract]
  • Dominik Rejman, Šárka Králíková, Zdeněk Točík, Radek Liboska and Ivan Rosenberg*
    Selective Cleavage of O-(Dimethoxytrityl) Protecting Group with Sodium Periodate
    2002, Vol. 67, Issue 4, pp. 502–508 [Abstract]
  • Jaroslav Zajíček, Ivan Rosenberg, Radek Liboska, Zdeněk Točík, G. Victor Fazakerley, Wilhelm Guschlbauer and Antonín Holý
    Conformational Studies on Diribonucleoside Monophosphate Analogs Containing a Nonisosteric, Isopolar, Phosphonate-Based Internucleotide Linkage
    1997, Vol. 62, Issue 1, pp. 83–98 [Abstract]
  • Andrei Guzaev, Harri Salo, Alex Azhayev and Harri Lönnberg
    Synthesis of oligonucleotide analogues by using phosphoramidite reagents derived from 2,2-bis(hydroxymethyl)malonates
    1996, Vol. 61, Special Issue, pp. S226–S229 [Abstract]
  • Magdalena Endová, Milena Masojídková and Ivan Rosenberg
    Synthesis of some derivatives of 1-[2-deoxy-3,5-O-(1-diethylphosphono)alkylidene-β-D-threo-pentofuranosyl]thymine substituted in the ω-position of the alkylidene moiety
    1996, Vol. 61, Special Issue, pp. S167–S170 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    A novel class of PME and HPMP derivatives of nucleobases modified in the heterocyclic moiety
    1996, Vol. 61, Special Issue, pp. S126–S128 [Abstract]
  • Šárka Králíková and Ivan Rosenberg
    The addition of phosphorous acid esters on the carbonyl group of 3'-ketonucleosides and nucleoside-5'-aldehydes: Synthesis of novel class of nucleotide analogs
    1996, Vol. 61, Special Issue, pp. S124–S125 [Abstract]
  • Dominik Rejman and Ivan Rosenberg
    Synthesis of 2'-alkoxy and 2'-aryloxy derivatives of 9-(2-phosphonomethoxyethyl)adenine (PMEA) and related compounds
    1996, Vol. 61, Special Issue, pp. S122–S123 [Abstract]
  • Harri Salo, Andrei Guzaev, Alex Azhayev and Harri Lönnberg
    Disulfide tethered solid supports for oligonucleotide synthesis: Preparation and a comparative study on the resistance to ammonolysis
    1996, Vol. 61, Special Issue, pp. S110–S111 [Abstract]
  • Harri Hakala, Pia Heinonen, Antti Iitia and Harri Lönnberg
    Covalent immobilization of oligonucleotides to microparticles. Quantitation of hybridization by time-resolved fluorescence detection on a single particle
    1996, Vol. 61, Special Issue, pp. S107–S109 [Abstract]
  • Ivan Rosenberg and Šárka Králíková
    A simple synthetic route to the preparation of 2-(1-phosphonoalkoxy)ethyl derivatives of heterocyclic bases as novel nucleotide analogs related to PMEA
    1996, Vol. 61, Special Issue, pp. S81–S84 [Abstract]
  • Zdeněk Točík, Iva Kavenová and Ivan Rosenberg
    Preparation of 4'-phosphonomethoxy derivatives of nucleosides: Addition of hydroxymethanephosphonic acid dialkyl esters to 4',5'-didehydronucleosides
    1996, Vol. 61, Special Issue, pp. S76–S80 [Abstract]
  • Mohamed Elzagheid, Alex Azhayev, Mikko Oivanen and Harri Lönnberg
    Synthesis of bis(3'-deoxyuridin-3'-yl) disulfide
    1996, Vol. 61, Special Issue, pp. S42–S44 [Abstract]
  • Satu Kuusela, Andrei Guzaev and Harri Lönnberg
    Zn2+ promoted hydrolysis of oligonucleotides
    1996, Vol. 61, Special Issue, pp. S30–S32 [Abstract]
  • Mikko Oivanen, Jaana Varila, Teemu Hankamaki, Leo H. Koole and Harri Lönnberg
    Hydrolysis and methanolysis of the phenyl ester of thymidine 3',5'-cyclic monophosphate: pH-dependent competition between PO and CO bond ruptures
    1996, Vol. 61, Special Issue, pp. S26–S29 [Abstract]
  • Mikko Oivanen, Mikko Ora and Harri Lönnberg
    The "thio effect" on the hydrolysis and transesterification of ribonucleoside phosphoesters
    1996, Vol. 61, Special Issue, pp. S1–S4 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA II. Racemic cis-Configured Derivatives
    1996, Vol. 61, Issue 5, pp. 778–790 [Abstract]
  • Radek Liboska, Milena Masojídková and Ivan Rosenberg
    Carbocyclic Phosphonate-Based Nucleotide Analogs Related to PMEA. I. Racemic trans-Configured Derivatives
    1996, Vol. 61, Issue 2, pp. 313–332 [Abstract]
  • Hana Dvořáková, Antonín Holý and Ivan Rosenberg
    Synthesis of Some 2'-C-Alkyl Derivatives of 9-(2-Phosphonomethoxyethyl)adenine and Related Compounds
    1994, Vol. 59, Issue 9, pp. 2069–2094 [Abstract]
  • Radek Liboska and Ivan Rosenberg
    Synthesis and antiviral activity of novel carbocyclic nucleoside and nucleotide analogs
    1993, Vol. 58, Special Issue, pp. S259–S261 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(9-Adeninyl)-5'-deoxy-L-pentofuranosyl]phosphonates: Conformationally restricted nucleotide analogs related to (S)-HPMPA
    1993, Vol. 58, Special Issue, pp. S256–S258 [Abstract]
  • Ivan Rosenberg and Radek Liboska
    Preparation of isosters of 9-[2-(phosphonomethoxy)ethyl] adenine
    1993, Vol. 58, Special Issue, pp. S94–S97 [Abstract]
  • Antonín Holý, Hana Dvořáková and Ivan Rosenberg
    Synthesis and antiviral activity of some 2'-C-alkyl derivatives of 9-(2-phosphonomethoxyethyl)adenine
    1993, Vol. 58, Special Issue, pp. S86–S90 [Abstract]
  • Sergei N. Mikhailov, Ekaterina V. Efimtseva, Sergei V. Meshkov and Harri Lönnberg
    Novel dioxolane analogues of 2',3'-dideoxynucleosides
    1993, Vol. 58, Special Issue, pp. S68–S70 [Abstract]
  • Harri Lönnberg
    Migration of hydrogen phosphate, monoalkyl phosphate, dialkyl phosphate and alkyl phosphonate groups between the 2'- and 3'-hydroxyl functions of ribonucleosides and their analogs
    1993, Vol. 58, Special Issue, pp. S9–S13 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxy-L-pentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. II. Synthesis of L-ribo and L-xylo Configurated Derivatives by Recyclization of Diethyl (5-RS)-[1,2-O-Isopropylidene-5-O-methanesulfonyl-D-pentofuranos-5-C-yl]phosphonates under Acidic Conditions
    1993, Vol. 58, Issue 9, pp. 2180–2196 [Abstract]
  • Miroslav Otmar, Ivan Rosenberg, Milena Masojídková and Antonín Holý
    [5-(Adenin-9-yl)-5-deoxypentofuranosyl]phosphonates - A Novel Type of Nucleotide Analogs Related to HPMPA. I. Derivatives with L-arabino, D-arabino, 2-Deoxy-L-erythro and 2-Deoxy-L-threo Configuration
    1993, Vol. 58, Issue 9, pp. 2159–2179 [Abstract]
  • Jiří Smrt, Luboš Arnold, Jan Svoboda, Roman Hák and Ivan Rosenberg
    Synthesis of Oligodeoxynucleotides Eliminating the Use of Acetonitrile
    1993, Vol. 58, Issue 7, pp. 1692–1698 [Abstract]
  • Tomas Cihlar, Ivan Votruba, Květoslava Horská, Radek Liboska, Ivan Rosenberg and Antonín Holý
    Metabolism of 1-(S)-(3-Hydroxy-2-phosphonomethoxypropyl)cytosine (HPMPC) in Human Embryonic Lung Cells
    1992, Vol. 57, Issue 3, pp. 661–672 [Abstract]
  • Janusz Stępiński, Lidia Grabowska, Edward Darżynkiewicz, Andrzej Temeriusz, Ryszard Stolarski, Stanley M. Tahara, David Shugar, Pia Järvinen and Harri Lönnberg
    Synthesis, conformation and hydrolytic stability of modified mRNA 5'-cap structures: P1,P3-dinucleoside triphosphates derived from guanosine and acyclic analogues of 7-methyl-, N2,7-dimethyl- and N2,N2,7-trimethylguanosines
    1990, Vol. 55, Special Issue, pp. S117–S120 [Abstract]
  • Mikko Oivanen, Tuula Viinamäki, Sergei Zavgorodny, Michael Polianski, Alex Azhayev, Arthur Van Aerschot, Piet Herdewijn and Harri Lönnberg
    Hydrolytic stability of potential antiviral nucleoside analogues: 3'-Substituted 2',3'-dideoxy- and 2',3'-didehydro-2',3'-dideoxyribonucleosides
    1990, Vol. 55, Special Issue, pp. S17–S20 [Abstract]
  • Jari Hovinen and Harri Lönnberg
    Kinetics and mechanism for acid-catalyzed opening of the imidazole ring of 6-unsubstituted purine nucleosides and their acyclic analogues
    1990, Vol. 55, Special Issue, pp. S9–S12 [Abstract]
  • Katarina Šedivá, Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Purine nucleoside phosphorylase: Isolation and characterization
    1990, Vol. 55, Issue 12, pp. 2987–2999 [Abstract]
  • Zbigniew Wieczorek, Edward Darżynkiewicz, Janusz Stępiński and Harri Lönnberg
    Fluorescence studies on P1,P3-dinucleoside triphosphates related to mRNA cap: Acidity and intramolecular stacking
    1990, Vol. 55, Issue 11, pp. 2765–2768 [Abstract]
  • Květa Horská, Aleš Cvekl, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    DNA-dependent RNA polymerase mediated formation of methylphosphonyl internucleotide linkage
    1990, Vol. 55, Issue 8, pp. 2100–2109 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-(2-phosphonylethoxy)ethyl) derivatives of heterocyclic bases
    1990, Vol. 55, Issue 3, pp. 809–818 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of (3-hydroxy-2-phosphonylmethoxypropyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 9, pp. 2470–2501 [Abstract]
  • Antonín Holý, Ivan Rosenberg and Hana Dvořáková
    Synthesis of N-(2-phosphonylmethoxyethyl) derivatives of heterocyclic bases
    1989, Vol. 54, Issue 8, pp. 2190–2210 [Abstract]
  • Aleš Cvekl, Květa Horská, Karel Šebesta, Ivan Rosenberg and Antonín Holý
    Trinucleotide AUA and UAU formation catalyzed by wheat germ RNA polymerase II
    1989, Vol. 54, Issue 3, pp. 811–818 [Abstract]
  • Ivan Rosenberg, Antonín Holý and Milena Masojídková
    Phosphonylmethoxyalkyl and phosphonylalkyl derivatives of adenine
    1988, Vol. 53, Issue 11, pp. 2753–2777 [Abstract]
  • Antonín Holý, Masahiko Nishizawa, Ivan Rosenberg and Ivan Votruba
    The effect of phosphonylmethyl analogs of ribonucleoside 5'-diphosphates on (E. coli) polynucleotide phosphorylase catalyzed reactions
    1987, Vol. 52, Issue 12, pp. 3042–3057 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of 9-(2-phosphonylmethoxyethyl)adenine and related compounds
    1987, Vol. 52, Issue 11, pp. 2801–2809 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of potential prodrugs and metabolites of 9-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2792–2800 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Synthesis of isomeric and enantiomeric O-phosphonylmethyl derivatives of 9-(2,3-dihydroxypropyl)adenine
    1987, Vol. 52, Issue 11, pp. 2775–2791 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Synthesis of phosphonylmethyl analogues of diribonucleoside monophosphates containing modified internucleotide bond
    1987, Vol. 52, Issue 10, pp. 2572–2588 [Abstract]
  • Milena Masojídková, Jaroslav Zajíček, Miloš Buděšínský, Ivan Rosenberg and Antonín Holý
    Conformational study on ribonucleoside O-phosphonylmethyl derivatives by 1H NMR spectroscopy
    1985, Vol. 50, Issue 8, pp. 1899–1905 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    An improved synthesis of S-adenosyl-L-homocysteine and related compounds
    1985, Vol. 50, Issue 7, pp. 1514–1518 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Phosphonylmethyl analogues of ribonucleoside 2',3'-cyclic phosphates and 2'(3')-nucleotide methyl esters: Synthesis and properties
    1985, Vol. 50, Issue 7, pp. 1507–1513 [Abstract]
  • Ivan Votruba, Antonín Holý and Ivan Rosenberg
    Affinity chromatography of rat liver S-adenosyl-L-homocysteine hydrolase
    1983, Vol. 48, Issue 9, pp. 2549–2557 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Donor activity of 5'-O-phosphonylmethyl analogues of ATP and GTP in the phosphorylation of uridine catalyzed by uridine kinase from mouse leukemic cells
    1983, Vol. 48, Issue 6, pp. 1783–1787 [Abstract]
  • Květa Horská, Ivan Rosenberg, Antonín Holý and Karel Šebesta
    5'-O-diphosphorylphosphonylmethylribonucleosides - A new group of DNA-dependent RNA polymerase inhibitors
    1983, Vol. 48, Issue 5, pp. 1352–1357 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Preparation of 2'(3')-O-phosphonylmethyl derivatives of ribonucleosides
    1983, Vol. 48, Issue 3, pp. 778–789 [Abstract]
  • Jiří Veselý, Ivan Rosenberg and Antonín Holý
    Inhibition by CTP and UTP analogues of uridine kinase from mouse leukemic cells
    1982, Vol. 47, Issue 12, pp. 3464–3469 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    Preparation of 5'-O-phosphonylmethyl analogues of nucleoside-5'-phosphates, 5'-diphosphates and 5'-triphosphates
    1982, Vol. 47, Issue 12, pp. 3447–3463 [Abstract]
  • Pavol Kois, Ivan Rosenberg and Antonín Holý
    Affinity chromatography of guanyloribonuclease from streptomyces aureofaciens
    1980, Vol. 45, Issue 10, pp. 2839–2846 [Abstract]
  • Ivan Rosenberg and Antonín Holý
    Nucleolytic enzymes of rape seedlings II. Unspecific acid phosphomonoester hydrolase
    1979, Vol. 44, Issue 11, pp. 3327–3340 [Abstract]
  • Antonín Holý and Ivan Rosenberg
    New pyrimidine (uridine) specific cyclizing 2'-ribonucleotidyltransferase and nonspecific decyclizing 2',3'-phosphodiesterase
    1979, Vol. 44, Issue 3, pp. 957–975 [Abstract]